منابع مشابه
Importance of estrogen metabolites.
T he influence of estrogen on blood pressure is complicated and sometimes contradictory. Premenopausal women have a lower incidence of hypertension, but recent clinical trials suggest that postmenopausal hormone replacement therapy does not necessarily decrease the risk of cardiovascular disease. Sexually dimorphic hypertension is evident in multiple animal models, yet only some indicate a crit...
متن کاملSources of estrogen and their importance.
In premenopausal women, the ovaries are the principle source of estradiol, which functions as a circulating hormone to act on distal target tissues. However, in postmenopausal women when the ovaries cease to produce estrogen, and in men, this is no longer the case, because estradiol is no longer solely an endocrine factor. Instead, it is produced in a number of extragonadal sites and acts local...
متن کاملAssociation of environmental chemicals & estrogen metabolites in children
BACKGROUND The prevalence of pediatric hormonal disorders and hormonally-sensitive cancers are rising. Chemicals including bisphenol A (BPA), phthalates, parabens, 4-nonylphenol (4NP) and triclosan have been linked to disruption of endocrine pathways and altered hormonal status in both animal and human studies. Additionally, changes in estrogen metabolism have been associated with pediatric end...
متن کاملCancer Morbidity in Rheumatoid Arthritis: Role of Estrogen Metabolites
Estrogen metabolites have been implicated in rheumatoid arthritis (RA) and cancer, although the mechanism remains unestablished. Some estrogen metabolites, which are used for the assessment of cancer risk, play an important role in RA. The pathways by which malignancies associated with RA remain elusive. Possible mechanism involves enzymatic or nonenzymatic oxidation of estrogen into catecholes...
متن کاملErratum to: Association of environmental chemicals & estrogen metabolites in children
© 2016 Ihde et al. Open Access This article is International License (http://creativecommons reproduction in any medium, provided you g the Creative Commons license, and indicate if (http://creativecommons.org/publicdomain/ze Author details The Deirdre Imus Environmental Health Center®, Hackensack University Medical Center, 30 Prospect Ave, Research Building, Hackensack, NJ 07601, USA. Departme...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2014
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.114.03382